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They work by stimulating insulin production, slowing down digestion, and promoting feelings of fullness, all of which contribute to healthy blood sugar levels

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Notably, semaglutide reduced BP in normotensive Glp1r Tie2+/+ and Glp1r Tie2–/– mice (Figure 3, G–I, and Supplemental Figure 5, D–F), indicating that GLP-1R expression in Tie2 + cells is not required for semaglutide-mediated reduction of BP in healthy mice